Posts Tagged ‘sirtuins’

“Ageless Quest” by Lenny Guarente

August 5, 2007


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MIT professor Lenny Guarente is a pioneer and leader in the study of the molecular biology of aging. This book is a popularized account of some of the early research that he and his students and post-docs conducted; research that helped move the study of aging from being a kind of slightly disreputable scientific backwater to one of the most dynamic and exciting fields of modern molecular biology. Guarente’s research focused on sirtuins, which are proteins that are now understood to retard aging in a wide variety of organisms, with mechanisms that vary depending on the organism.”

Ageless Quest” is an easy read and a great introduction to the field. It had a surprising amount of impact on me; after reading this book I decided that I wanted to learn more about what was happening in this very important field, so I audited an MIT reading course on the molecular biology of aging taught by Angeiszka Czopik and Danica Chen, two post-docs in Prof. Guarente’s lab, and then I attended the 2006 Summer School Course on the molecular biology of aging at Woods Hole’s famous Marine Biological Laboratory, organized by Gary Ruvkun and Steve Austad.

This book probably won’t have that big an impact on you! It’s a pretty light book weighing in at only 154 pages; but you can learn a lot whether or not you have a background in biology.

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